Package: TIGERr Type: Package Title: Technical Variation Elimination with Ensemble Learning Architecture Version: 1.0.2 Author: Siyu Han [aut, cre], Jialing Huang [aut], Francesco Foppiano [aut], Cornelia Prehn [aut], Jerzy Adamski [aut], Karsten Suhre [aut], Ying Li [aut], Giuseppe Matullo [aut], Freimut Schliess [aut], Christian Gieger [aut], Annette Peters [aut], Rui Wang-Sattler [aut] Maintainer: Siyu Han Acknowledgments: TAI Yun-hsiu, WANG Ruoyu, CHENG Ming, GUO Yuan, LI Han, FAN Linrui Description: The R implementation of TIGER. TIGER integrates random forest algorithm into an innovative ensemble learning architecture. Benefiting from this advanced architecture, TIGER is resilient to outliers, free from model tuning and less likely to be affected by specific hyperparameters. TIGER supports targeted and untargeted metabolomics data and is competent to perform both intra- and inter-batch technical variation removal. TIGER can also be used for cross-kit adjustment to ensure data obtained from different analytical assays can be effectively combined and compared. Reference: Han S. et al. (2022) . License: GPL (>= 3) Depends: R (>= 3.5.0) Imports: parallel (>= 2.1.0), pbapply (>= 1.4-3), ppcor (>= 1.1), randomForest (>= 4.6-14), stats (>= 3.0.0) BugReports: https://github.com/HAN-Siyu/TIGER/issues Encoding: UTF-8 LazyData: true RoxygenNote: 7.3.1 Repository: https://han-siyu.r-universe.dev Date/Publication: 2025-08-06 22:18:42 UTC RemoteUrl: https://github.com/han-siyu/tiger RemoteRef: HEAD RemoteSha: 8227544bfce0f1d89e0317ce20cdbd31128d5726 NeedsCompilation: no Packaged: 2026-07-02 06:20:17 UTC; root