{
  "_id": "6a478d126527f6f71fa0e39c",
  "Package": "TIGERr",
  "Type": "Package",
  "Title": "Technical Variation Elimination with Ensemble Learning\nArchitecture",
  "Version": "1.0.2",
  "Author": "Siyu Han [aut, cre], Jialing Huang [aut], Francesco Foppiano\n[aut], Cornelia Prehn [aut], Jerzy Adamski [aut], Karsten Suhre\n[aut], Ying Li [aut], Giuseppe Matullo [aut], Freimut Schliess\n[aut], Christian Gieger [aut], Annette Peters [aut], Rui\nWang-Sattler [aut]",
  "Maintainer": "Siyu Han <han.siyu@outlook.com>",
  "Acknowledgments": "TAI Yun-hsiu, WANG Ruoyu, CHENG Ming, GUO Yuan, LI\nHan, FAN Linrui",
  "Description": "The R implementation of TIGER. TIGER integrates random\nforest algorithm into an innovative ensemble learning\narchitecture. Benefiting from this advanced architecture, TIGER\nis resilient to outliers, free from model tuning and less\nlikely to be affected by specific hyperparameters. TIGER\nsupports targeted and untargeted metabolomics data and is\ncompetent to perform both intra- and inter-batch technical\nvariation removal. TIGER can also be used for cross-kit\nadjustment to ensure data obtained from different analytical\nassays can be effectively combined and compared. Reference: Han\nS. et al. (2022) <doi:10.1093/bib/bbab535>.",
  "License": "GPL (>= 3)",
  "BugReports": "https://github.com/HAN-Siyu/TIGER/issues",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "RoxygenNote": "7.3.1",
  "Repository": "https://han-siyu.r-universe.dev",
  "Date/Publication": "2025-08-06 22:18:42 UTC",
  "RemoteUrl": "https://github.com/han-siyu/tiger",
  "RemoteRef": "HEAD",
  "RemoteSha": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-07-02 06:20:17 UTC",
    "User": "root"
  },
  "_user": "han-siyu",
  "_type": "src",
  "_file": "TIGERr_1.0.2.tar.gz",
  "_fileid": "https://r2.ropensci.org/37de264c8ad17e8c1607da94883cc4411dabe9f9a37a935648380b2394e32131",
  "_filesize": 193307,
  "_sha256": "37de264c8ad17e8c1607da94883cc4411dabe9f9a37a935648380b2394e32131",
  "_expires": "2026-10-11T10:21:06.000Z",
  "_created": "2026-07-02T06:20:17.000Z",
  "_published": "2026-07-03T10:21:06.889Z",
  "_jobs": [
    {
      "job": 84979516159,
      "time": 106,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "8030543766"
    },
    {
      "job": 84979516108,
      "time": 124,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8030549078"
    },
    {
      "job": 84979516628,
      "time": 170,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "8030556625"
    },
    {
      "job": 84979516490,
      "time": 158,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8030550776"
    },
    {
      "job": 84979515684,
      "time": 131,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8030510949"
    },
    {
      "job": 84979516396,
      "time": 102,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "8030542283"
    },
    {
      "job": 84979516213,
      "time": 64,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "8030531386"
    },
    {
      "job": 84979516651,
      "time": 75,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "8030534453"
    },
    {
      "job": 84979516156,
      "time": 69,
      "config": "windows-release",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "8030533448"
    }
  ],
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266",
  "_status": "success",
  "_upstream": "https://github.com/han-siyu/tiger",
  "_commit": {
    "id": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
    "author": "Han, Siyu <hansy15@mails.jlu.edu.cn>",
    "committer": "Han, Siyu <hansy15@mails.jlu.edu.cn>",
    "message": "update: TIGER v1.0.2\n",
    "time": 1754518722
  },
  "_maintainer": {
    "name": "Siyu Han",
    "email": "han.siyu@outlook.com",
    "login": "han-siyu",
    "linkedin": "in/han-siyu",
    "description": "Computational Health Center, Helmholtz Munich - German Research Center for Environmental Health",
    "uuid": 16144249
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.5.0",
      "role": "Depends"
    },
    {
      "package": "parallel",
      "version": ">= 2.1.0",
      "role": "Imports"
    },
    {
      "package": "pbapply",
      "version": ">= 1.4-3",
      "role": "Imports"
    },
    {
      "package": "ppcor",
      "version": ">= 1.1",
      "role": "Imports"
    },
    {
      "package": "randomForest",
      "version": ">= 4.6-14",
      "role": "Imports"
    },
    {
      "package": "stats",
      "version": ">= 3.0.0",
      "role": "Imports"
    }
  ],
  "_owner": "han-siyu",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-32",
      "n": 1
    }
  ],
  "_tags": [],
  "_stars": 6,
  "_contributors": [
    {
      "user": "han-siyu",
      "count": 56,
      "uuid": 16144249
    }
  ],
  "_userbio": {
    "uuid": 16144249,
    "type": "user",
    "name": "Han, Siyu",
    "followers": 11,
    "description": "Computational Health Center, Helmholtz Munich - German Research Center for Environmental Health"
  },
  "_downloads": {
    "count": 247,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/TIGERr"
  },
  "_devurl": "https://github.com/han-siyu/tiger",
  "_searchresults": 3,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "extra/TIGERr.html",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/han-siyu/tiger",
  "_realowner": "han-siyu",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.1.0",
      "date": "2021-09-02"
    },
    {
      "version": "1.0.0",
      "date": "2022-01-06"
    }
  ],
  "_exports": [
    "compute_RSD",
    "compute_targetVal",
    "run_TIGER",
    "select_variable"
  ],
  "_datasets": [
    {
      "name": "FF4_qc",
      "title": "Accompanying QC samples of KORA FF4 (demo data)",
      "object": "FF4_qc",
      "class": [
        "data.frame"
      ],
      "fields": [
        "sampleID",
        "sampleType",
        "plateID",
        "injectionOrder",
        "wellPosition",
        "C0",
        "C2",
        "C3",
        "C4",
        "C5",
        "C10",
        "C12",
        "C14.1",
        "C14.2",
        "C16",
        "C18",
        "C18.1",
        "C18.2",
        "Arg",
        "Gly",
        "Met",
        "Orn",
        "Pro",
        "Ser",
        "Thr",
        "Tyr",
        "Val",
        "lysoPC.a.C16.0",
        "lysoPC.a.C16.1",
        "lysoPC.a.C17.0",
        "lysoPC.a.C18.0",
        "lysoPC.a.C18.1",
        "lysoPC.a.C18.2",
        "lysoPC.a.C20.3",
        "lysoPC.a.C20.4",
        "PC.aa.C28.1",
        "PC.aa.C30.0",
        "PC.aa.C32.0",
        "PC.aa.C32.1",
        "PC.aa.C32.2",
        "PC.aa.C32.3",
        "PC.aa.C34.1",
        "PC.aa.C34.3",
        "PC.aa.C34.4",
        "PC.aa.C36.1",
        "PC.aa.C36.2",
        "PC.aa.C36.3",
        "PC.aa.C36.4",
        "PC.aa.C36.5",
        "PC.aa.C36.6",
        "PC.aa.C38.0",
        "PC.aa.C38.3",
        "PC.aa.C38.4",
        "PC.aa.C38.5",
        "PC.aa.C38.6",
        "PC.aa.C40.2",
        "PC.aa.C40.3",
        "PC.aa.C40.4",
        "PC.aa.C40.5",
        "PC.aa.C42.0",
        "PC.aa.C42.1",
        "PC.aa.C42.2",
        "PC.aa.C42.4",
        "PC.aa.C42.5",
        "PC.aa.C42.6",
        "PC.ae.C32.1",
        "PC.ae.C32.2",
        "PC.ae.C34.0",
        "PC.ae.C34.1",
        "PC.ae.C34.2",
        "PC.ae.C34.3",
        "PC.ae.C36.1",
        "PC.ae.C36.2",
        "PC.ae.C36.3",
        "PC.ae.C36.4",
        "PC.ae.C36.5",
        "PC.ae.C38.0",
        "PC.ae.C38.2",
        "PC.ae.C38.3",
        "PC.ae.C38.4",
        "PC.ae.C38.5",
        "PC.ae.C38.6",
        "PC.ae.C40.1",
        "PC.ae.C40.2",
        "PC.ae.C40.3",
        "PC.ae.C40.4",
        "PC.ae.C40.5",
        "PC.ae.C40.6",
        "PC.ae.C42.1",
        "PC.ae.C42.2",
        "PC.ae.C42.3",
        "PC.ae.C42.4",
        "PC.ae.C42.5",
        "PC.ae.C44.4",
        "PC.ae.C44.5",
        "PC.ae.C44.6",
        "SM..OH..C14.1",
        "SM..OH..C16.1",
        "SM..OH..C22.1",
        "SM..OH..C22.2",
        "SM..OH..C24.1",
        "SM.C16.0",
        "SM.C16.1",
        "SM.C18.0",
        "SM.C18.1",
        "SM.C20.2",
        "SM.C24.1",
        "H1"
      ],
      "rows": 232,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "compute_RSD",
      "title": "Compute RSD (relative standard deviation)",
      "topics": [
        "compute_RSD"
      ]
    },
    {
      "page": "compute_targetVal",
      "title": "Compute target values for ensemble learning architecture",
      "topics": [
        "compute_targetVal"
      ]
    },
    {
      "page": "FF4_qc",
      "title": "Accompanying QC samples of KORA FF4 (demo data)",
      "topics": [
        "FF4_qc"
      ]
    },
    {
      "page": "run_TIGER",
      "title": "Run TIGER to eliminate technical variation",
      "topics": [
        "run_TIGER"
      ]
    },
    {
      "page": "select_variable",
      "title": "Select variables for ensemble learning architecture",
      "topics": [
        "select_variable"
      ]
    }
  ],
  "_readme": "https://github.com/han-siyu/tiger/raw/HEAD/README.md",
  "_rundeps": [
    "MASS",
    "pbapply",
    "ppcor",
    "randomForest"
  ],
  "_score": 3.4771212547196626,
  "_indexed": true,
  "_nocasepkg": "tigerr",
  "_universes": [
    "han-siyu"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-07-02T06:22:04.000Z",
      "distro": "resolute",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/25befc50f0684dcdf269201770fba844bb7f1735396b43df4f9c19945e65387c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.0.2",
      "date": "2026-07-02T06:22:21.000Z",
      "distro": "resolute",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/47644ce306d34983f8969d3173d72a0b4ba9abd55c765ece32f51fbe5ab188fd",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.0.2",
      "date": "2026-07-02T06:22:54.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/b83518aafc0feff88998bc799521f6565a7fe497a27e55a653800537beb4859b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.0.2",
      "date": "2026-07-02T06:22:24.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/60a0f7ed0bcb92c4da52751ce3265c0274b33427bcb5b89d249ba7eb07127303",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.0.2",
      "date": "2026-07-02T06:22:14.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/0b29300b3819d3524c278b778a904caafb9459a8ca05572de376db16eb0bdb66",
      "status": "success",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-07-02T06:21:17.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/e13ffb86c0ea0f3a65c2c0d465748cdcc409dc25a60e1adf65d0887c17499d4a",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-07-02T06:21:23.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/c51929d6f809ef44ef2098bd2d0a42774d94aed348d9a97c159c857af7c2e00c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.0.2",
      "date": "2026-07-02T06:21:22.000Z",
      "commit": "8227544bfce0f1d89e0317ce20cdbd31128d5726",
      "fileid": "https://r2.ropensci.org/e811661c56d89d8da3e833a164590f09872672514ff802687fa9720c4db85a32",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/han-siyu/actions/runs/28569735266"
    }
  ]
}